Emergent Computer Literacy

As more children are using computers at a younger age, it is necessary to understand how we can support their interactions for optimal experiences and learning. This book examines computer experiences of children living with their parents in the home setting. Robinson adds exceptional insight into how children become literate in a technological society and offers necessary tools for researchers and academics to understand how young children interact with computers both at home and in a school setting.

“A Choice Outstanding Book of 2009 "The book is essential for anyone studying literacy or looking for suggestions on curricular inclusion of computer literacy. Quantitative and qualitative researchers will find this book valuable for the design and execution of the study. Robinson's text is incisive and most immediately complementary to scholarship in education, English, psychology, sociology and information science... Highly recommended."--L.H. Taylor Jr., Choice(2009), Vol. 46, No. 11 "Emergent Computer Literacyis an admirably concise study with a number of important implications for future research on children and computer literacy in the "information age". The book will enlighten both researchers and parents alike and ask them to reconsider the development of their children and their assimilation into a technologically driven society. I recommend this book to researchers and also parents as an important starting point to consider the role of the new digital literacies affecting children's education around the world."--Jeremy White, International Journal of Emerging Technologies and Society( 2009), Vol. 7, No. 2 ciety. I recommend this book to researchers and also parents as an important starting point to consider the role of the new digital literacies affecting children's education around the world."--Jeremy White, International Journal of Emerging Technologies and Society( 2009), Vol. 7, No. 2”

A Choice Outstanding Book of 2009 "The book is essential for anyone studying literacy or looking for suggestions on curricular inclusion of computer literacy. Quantitative and qualitative researchers will find this book valuable for the design and execution of the study. Robinson's text is incisive and most immediately complementary to scholarship in education, English, psychology, sociology and information science... Highly recommended."--L.H. Taylor Jr., Choice (2009), Vol. 46, No. 11 "Emergent Computer Literacy is an admirably concise study with a number of important implications for future research on children and computer literacy in the "information age". The book will enlighten both researchers and parents alike and ask them to reconsider the development of their children and their assimilation into a technologically driven society. I recommend this book to researchers and also parents as an important starting point to consider the role of the new digital literacies affecting children's education around the world."--Jeremy White, International Journal of Emerging Technologies and Society ( 2009), Vol. 7, No. 2

Helen Mele Robinson is Assistant Professor in the Education Department at CUNY, The College of Staten Island.  She has published journal articles in Perspective: The New York Journal of Adult Learning.

Nuclear Receptors (NRs) are ligand-induced activated transcription factors that are involved in numerous biological processes. Since the 90's when the first structures were determined by means of X-ray diffraction, the number has increased considerably. Moreover several "omics" projects have opened up great opportunities for the discovery of new targets, the characterization of abnormal protein patterns, the selection of "tailored" drugs and the evaluation of drug efficacy even with a lack of structural data. Furthermore, structure-based drug design, computational methods for in silico screening and nanobiotechnology-based tools are simplifying this time-consuming and expensive research of identifying lead compounds and, possibly new drugs. Biological interactions such as those that occur between a protein and ligand are concerted events where flexible molecules interact. Understanding the flexibility of large molecules or biological complexes is of primary importance to help define the right model to approximate the reality for drug discovery, virtual screening and food safety analysis. NRs are known as flexible targets, with many structural similarities, in particular for their Ligand Binding Domain. To understand the behaviour of NRs, it is mandatory to approach the subject from a different perspective. The aim of this book is to provide a state-of- the-art review on investigations into Nuclear Receptors. The contents provide an introduction to their structure and function, a critical overview of experimental structural data as a base for modeling, development of theoretical approaches to modeling and computational studies to predict interactions with small ligands, in vitro and in vivo experiments to validate computational simulations, experimental applications, and as targets for endocrine disruptor screening.

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