A Guide to Outcome Modeling In Radiotherapy and Oncology by Issam El Naqa, Hardcover, 9781498768054 | Buy online at The Nile
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A Guide to Outcome Modeling In Radiotherapy and Oncology

Listening to the Data

Author: Issam El Naqa   Series: Series in Medical Physics and Biomedical Engineering

A Guide to Outcome Modeling In Radiotherapy and Oncology
Hardcover

This book serves as a tutorial for newcomers to the field of outcome modeling; including in-depth how-to recipes on modeling artistry and providing instructions on how such models can approximate the physical and biological realities of clinical treatment.

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PRODUCT INFORMATION

Summary

This book serves as a tutorial for newcomers to the field of outcome modeling; including in-depth how-to recipes on modeling artistry and providing instructions on how such models can approximate the physical and biological realities of clinical treatment.

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Description

This book explores outcome modeling in cancer from a data-centric perspective to enable a better understanding of complex treatment response, to guide the design of advanced clinical trials, and to aid personalized patient care and improve their quality of life. It contains coverage of the relevant data sources available for model construction (panomics), ranging from clinical or preclinical resources to basic patient and treatment characteristics, medical imaging (radiomics), and molecular biological markers such as those involved in genomics, proteomics and metabolomics. It also includes discussions on the varying methodologies for predictive model building with analytical and data-driven approaches.

This book is primarily intended to act as a tutorial for newcomers to the field of outcome modeling, as it includes in-depth how-to recipes on modeling artistry while providing sufficient instruction on how such models can approximate the physical and biological realities of clinical treatment. The book will also be of value to seasoned practitioners as a reference on the varying aspects of outcome modeling and their current applications.

Features:

  • Covers top-down approaches applying statistical, machine learning, and big data analytics and bottom-up approaches using first principles and multi-scale techniques, including numerical simulations based on Monte Carlo and automata techniques
  • Provides an overview of the available software tools and resources for outcome model development and evaluation, and includes hands-on detailed examples throughout
  • Presents a diverse selection of the common applications of outcome modeling in a wide variety of areas: treatment planning in radiotherapy, chemotherapy and immunotherapy, utility-based and biomarker applications, particle therapy modeling, oncological surgery, and the design of adaptive and SMART clinical trials

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About the Author

Issam El Naqa is an Associate Professor of Radiation Oncology at the University of Michigan at Ann Arbor, USA.

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Product Details

Publisher
Taylor & Francis Inc | CRC Press Inc
Published
2nd March 2018
Pages
392
ISBN
9781498768054

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